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Monitoring for Rejection after Liver Transplant

Rejection is your body's normal reaction to your transplanted organ. Your body's response to any foreign object is to destroy it. Immune cells immediately start fighting this foreign body. New organ rejection is normal and can occur at any time after a transplant.

Nearly all patients will experience one or more episodes of rejection during their recovery period. If left unchecked, the immune cells can damage a new organ. Most cases of rejection are easily treated. Constant monitoring for rejection - and prompt medical attention - will keep your new organ functioning.

Symptoms of liver rejection include:

  • Light-colored stools
  • Dark-colored urine
  • Yellow eyes and skin
  • Fatigue
  • Lethargy
  • Shortness of breath
  • Sometimes fever
  • Abdominal pain
  • Elevated liver function tests

Any symptom should be taken very seriously. Rejection may be mild or severe. In most cases, rejection can be controlled if treated promptly. A biopsy may be required to make a definitive diagnosis. If you are having a rejection episode, you may be admitted to the hospital for treatment.

If you experience any symptoms of rejection, contact your transplant nurse or physician immediately.

If you received your organ transplant at the Hospital of the University of Pennsylvania and are experiencing signs of organ rejection, call the transplant nurse at 215-662-6200 during office hours, 9:00 am to 5:00 pm. After 5:00 pm, call the main hospital number, 215-662-4000, and ask for the transplant coordinator on call.

Revised by Kim Olthoff, MD
Last updated February 2006

 


 

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