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TORS Dramatically Improves Surgical Treatment for Head & Neck Cancer

May / June 2006

New surgical technique pioneered in Philadelphia offers patient benefits.

Penn surgeons have pioneered the use of transoral robotic surgery (TORS), completing the largest and most comprehensive study regarding the effectiveness of TORS for oral and laryngopharyngeal benign and malignant lesions. Penn's Center for Head and Neck Surgery is the only center in the world with an Institutional Review Board-approved study and the only center currently reporting on TORS.

“In the last decade, we've seen a tremendous growth in robotic surgery, especially in cardiac and urologic procedures. It made us consider how robotics could be applied to surgical treatment for head and neck cancer,” says Bert O'Malley, MD, chair, Department of Otorhinolaryngology at the Hospital of the University of Pennsylvania and co-director, Penn's Center for Head and Neck Cancer.

“Surgical treatment for cancers of the mouth and throat can involve breaking the jawbone, ear-to-ear incisions, tracheotomy, speech and swallowing difficulties and cosmetic scarring. For some patients, TORS can mean less surgery, less deformity and a faster rehabilitation in functional recovery,” says Gregory Weinstein, MD, vice chairman, Department of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania; director, Head and Neck Surgery Division and Head and Neck Surgery Clinic and co-director, Penn’s Center for Head and Neck Cancer.

How it Works
The Penn da Vinci surgical robotic system has three main components: a mechanical robot with four multi-jointed arms (three are used for TORS: one with an endoscope and two with instruments), a computer command center several feet from the patient and a 3D video monitor that provides a magnified view of the surgical site inside the patient. Equipped with a special, double-telescopic endoscope, the viewfinder allows surgeons to see the surgical site more closely than human vision allows and to work at a smaller scale of detail than conventional surgery permits.

“The end of the instrument basically moves exactly like your hand,” says Dr. Weinstein. “It is as if your hands are miniaturized in whatever small cavity you are operating. In standard laproscopic surgery, you're still about 20 inches away from the surgical site, if you consider the instruments you're holding and the depth of the area in which you're operating. That distance prevents you from achieving full wrist motion but the difficulty is non-existent in TORS. The system has perfect movement with six degrees of freedom so it actually completely reflects the wrist.”

In addition, “TORS provides superb visualization of the operative field as well as three-dimensional vision,” says Dr. O'Malley. “Those who criticize the technique say that it does not provide any sense of tactile feeling. But the visualization it provides transcends the true sense of touch. Nonetheless, mechanical resistance provided by the instrumentation gives you a sense of touch that is linked directly to the surgeon's hand. It allows for very fine and delicate surgery.”

Contraindications and Risks
At this time, Penn researchers have found no specific contraindications for TORS. If a patient is a good surgical candidate, he or she may be a good candidate for TORS. “The only exceptions, so far, have been patients who have an anatomy that interferes with the success of the procedure,” says Dr. Weinstein. “For example, if a patient has a very tiny jaw, it may not be realistic to operate transorally.”

The safety and risk profile appears to be similar to conventional transoral surgery. Initial studies regarding management of hemostasis during TORS showed that there are no additional difficulties with the robotic technique. Researchers found effective hemostasis of both large and small vessels could be maintained using surgical hemoclips and electrocautery. “We're using the same blood management techniques used in open surgery,” says Dr. Weinstein. “We have not found any risk of increased bleeding or difficulty controlling bleeding.”

Clinical Impressions
In some cases, robotic surgical resection is used in combination with radiation and chemotherapy. The study focuses primarily on the surgeons' ability to access the lesion for resection with TORS and secondarily on issues such as safety and quality of life. “The entire TORS procedure is typically performed in about one to two hours, compared to six to 12 hours for standard open procedures,” says Dr. O'Malley. “The shorter surgery, smaller incisions and reduced bleeding may improve overall recovery rates for patients.”

Penn researchers are speaking both nationally and internationally about the technique they've pioneered. “We've received an amazing response,” says Dr. O'Malley.

Currently, patients who may benefit from TORS can only receive the surgery by participating in Penn's IRB-approved clinical trial. Eligible participants must be at least 18 years old and present with indications for diagnostic and therapeutic approaches for benign and malignant diseases of the oral cavity or laryngopharynx. Exclusion criteria include unexplained fever and/or treated, active infection; pregnancy; previous head and neck surgery preventing transoral/robotic procedures; and the presence of medical conditions contraindicating general anesthesia or transoral surgical approaches.

Online Consultation
Penn otorhinolaryngologists are available for consultation on any case. For more information, please call PENNHealth at 1-800-789-PENN. You can also visit ENTconsult.org, the referring health care professional's online connection to the University of Pennsylvania Health System's Department of Otorhinolaryngology – Head and Neck Surgery.

After registering for a secure account, physicians and advanced health care practitioners can:

  • Request Patient Referrals
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Prompt attention and rapid communication can be expected from our team. Click here to set-up your account today.

 


Referring Physicians: To speak with a Penn physician or refer a patient, contact PennHealth through the secure online referral form or by calling
1-800-789-PENN (7366).

   
   

 

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