Research
Researchers are looking for ways to improve the
drug therapies used to treat fibroids. Of particular
interest are ways to reduce the side effects of
the GnRH analogues (synthetic hormones) which
are helpful in shrinking fibroids, but can cause
menopausal symptoms such as hot flashes, sleep
disturbances, mood changes, vaginal dryness, and
increased risk for osteoporosis (weakening of
the bone).
One of the most promising therapies currently
being investigated is "add-back" hormone
replacement therapy in which a medication containing
a low dose estrogen is taken in conjunction with
the GnRH analogues. This combination may alleviate
many of the menopausal symptoms without compromising
the ability of the hormones to shrink the fibroid.
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