Penn Gynocologic Oncology Care Newsletter
 

Winter 2007

Answers to Your Questions about Cervical Cancer
Do You Need an HPV Test?
Now Available: The HPV Vaccine
HPV Vaccine - A New Direction in Cancer Prevention
 
Care Pages
 

Do You Need an HPV Test?

The human papillomavirus (HPV), one of the most common sexually transmitted infections, is the leading cause of cervical cancer. HPV affects approximately 80 percent of all adults by the time they reach age 50.

For years, the standard procedure used by gynecologists to detect cervical cancer has been the Pap test. Many women believe that the Pap test is an adequate screening test for cervical cancer, but recent studies suggest that the Pap test alone may not find the abnormal cells that can lead to cancer. This is why more physicians are using a test for HPV, in addition to a Pap test, as a screening for cervical cancer.

What is HPV?
HPV (human papillomavirus) is a common viral infection, not a disease, and is usually harmless. There are more than 100 types of HPV, divided into low- and high-risk categories.

Low-risk HPV does not lead to cancer but may cause dysplasia (abnormal cells in the cervix that can lead to cancer if not treated) and/or genital warts. There are as many as a dozen high-risk HPV infections that are responsible for cancer of the cervix.

Cervical cancer is almost always caused by the human papillomavirus. There is no cure for HPV, but since a woman’s immune system fights off most HPV infections, there is no need to feel alarmed if you have the virus.

Michelle Vichnin, MD, a gynecologist with the University of Pennsylvania Health System states, “Millions of women are affected with HPV, yet only a few thousand develop cervical cancer each year. It is important to know if your HPV infection falls into the low- or high-risk category and to have health problems caused by the virus such as genital warts, dysplasia or cervical cancer treated.”

Who should have an HPV test?
Not all women need an HPV test. “The U.S. Food and Drug Administration has approved the HPV test for routine screening of women age 30 years and older, when done with a Pap smear. It is also recommended that women under age 30 have the HPV test if their Pap results are uncertain,” states Dr. Vichnin.

The HPV test is performed during an annual gynecologic exam. Most insurance companies pay for routine HPV testing, along with a Pap test, for women 30 years of age and older. Dr. Vichnin continues, “HPV and Pap testing is recommended because HPV can be hidden in genital cells long after a woman was initially exposed to it.”

Risk factors for HPV exposure include early age at first intercourse, multiple sexual partners, and cigarette smoking. It is not possible to determine exactly when a woman became infected with HPV.

Why do I need an HPV test and a Pap test?
The accuracy of the Pap test, a test that examines cells in cervical tissue, is dependent upon the expertise and interpretation of the clinician reading it. Often tests are considered “abnormal” and a woman must undergo anxious wait periods and be retested.

The HPV test uses automated technology to detect the presence of the HPV virus. In addition, the HPV test can clarify certain categories of a Pap test’s diagnosis. Thus having both the HPV and Pap tests together offers the most accurate results.

“A woman over age 30, with a normal Pap test and a negative HPV test, is 99.7 percent unlikely to develop cervical cancer in the next three years,” notes Dr. Vichnin. “Therefore, the current recommendation for HPV testing is every three years.”

The Department of Obstetrics and Gynecology at the University of Pennsylvania offers gynecology and gynecologic oncology services throughout the Philadelphia region. To make an appointment with a Penn Ob/Gyn Care physician, call 1-800-789-PENN (7366) or request an appointment online.


Need an appointment? Request one online 24 hours/day, 7 days/week or call 800-789-PENN (7366) to speak to a referral counselor.

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