Penn Fertility Care e-newsletter
 

Spring 2006

 

 

Weight and Fertility

 

Research and Clinical Trials at Penn Fertility Care
 

Weight and Fertility

One in seven couples in the United States experience fertility problems, which can stem from a variety of health issues. One health issue associated with infertility is a person's body weight – in particular, the female partner's weight. Being overweight or underweight can greatly affect a woman's ability to conceive.

How does being overweight affect fertility?
Women who are overweight or obese may have imbalances in reproductive hormones, which affect menstrual cycles and prevent ovulation. Clarisa Gracia, MD, a reproductive endocrinologist at Penn Fertility Care states, “The relationship between obesity and reproductive problems is complicated.However, insulin resistance and estrogen production from fat cells can affect the ovary and prevent eggs from being released every month. This condition is called anovulation. If by chance an egg is released, the egg may not be healthy enough to result in a pregnancy.”

Dr. Gracia continues, “Fertility problems related to weight usually affect women who are at least 10 percent over their ideal body weight. While fertility treatments are available to improve the chances of becoming pregnant, weight loss alone may correct infertility in some cases.”

A condition known as polycystic ovary syndrome (PCOS) is associated with obesity and affects a woman's ability to conceive. PCOS results from a hormonal imbalance that leads to excess production of androgens by the ovary , which can prevent or delay ovulation.

Symptoms of PCOS
The following symptoms are related to PCOS:

  • Irregular, scanty or absent menstrual periods
  • Increased levels of male hormones
  • Obesity or weight gain
  • Insulin resistance
  • Infertility
  • Excess hair growth (hirsutism)
  • High blood pressure (readings over 140/90)
  • Acne
  • Male pattern baldness
  • Dark patches of skin on back of neck, under arms, groin

Weight reduction is an important factor in the treatment of PCOS. Maintaining good general health through careful food choices and exercise can help to eliminate the complications of obesity and diabetes in women with PCOS. Weight loss may improve fertility and pregnancy outcomes.

How can I tell if I am at a healthy weight?
A good way to assess your weight is to calculate your Body Mass Index (BMI). Your BMI estimates whether you are at a healthy weight.

BMI Categories:

  • Below 18.5 = Underweight
  • 18.5 - 24.9 = Healthy
  • 25.0 - 29.9 = Overweight
  • 30.0 - 39.9 = Obese
  • Over 40 = Morbidly Obese

In general, the term “overweight” typically refers to a weight that is 10 percent above the expected body weight for height and build. The term “obese” refers to being 20 percent over the target weight.

Can weighing too little lower my chances of getting pregnant?
The degree to which weight loss affects fertility will vary. The American Society for Reproductive Medicine (ASRM) states, “In mild cases, the ovaries may still produce and release eggs, but the lining of the uterus may not be ready to receive a fertilized egg because of inadequate ovarian hormone production. In more severe cases, ovulation does not occur, and menstrual cycles are irregular or absent. In men, low weight or weight loss may lead to decreased sperm function or sperm count. If low weight or weight loss has been identified as the cause of one's infertility, the preferred treatment would be to stop losing weight or even to gain weight if needed.”

If a woman is dealing with a weight and eating disorder, she should talk with her health care provider to determine her best course of achieving a healthy lifestyle and ultimately the return of her fertility.

Fertility medications can be used as an alternate treatment for fertility issues related to a woman being over or underweight. Dr. Gracia advises, “A variety of fertility medications are available to enhance fertility related weight problems. In general, these medications stimulate the production and release of eggs from the ovaries. Often these medications are followed by inseminating sperm into a woman's uterus to improve the chances of pregnancy. If these methods do not result in pregnancy, it may be necessary for a woman to pursue in vitro fertilization.”

It should be noted that while fertility drugs can help a woman achieve a pregnancy, the use of these drugs can be complicated, at times expensive, and can cause multiple pregnancies.

If I conceive and am still over or underweight, are there risks to the pregnancy?
When pregnancy is achieved, excessive weight increases the risks associated with pregnancy. “Unfortunately, overweight women appear to have a higher risk of miscarriage as well," notes Dr. Gracia. "In addition, a pregnancy can be more complex due to gestational diabetes and other complications.” Your reproductive endocrinologist or ob/gyn may refer you to a maternal fetal medicine specialist, a physician who specializes in high-risk pregnancy care.

Women have control over many of the things that can affect fertility. The lifestyle choices of smoking, drinking caffeine or alcohol, unhealthy food choices, weight, and sexual practices have an impact on future fertility. To achieve the best success at conceiving, focus on maintaining a healthy lifestyle.


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