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Pertussis

Pertussis

Respiratory system overview
Respiratory system overview

Definition:

Pertussis is a highly contagious bacterial disease that causes uncontrollable, violent coughing. The coughing can make it hard to breathe.  A deep "whooping" sound is often heard when the patient tries to take a breath.

Alternative Names:

Whooping cough

Causes, incidence, and risk factors:

Pertussis, or whooping cough, is an upper respiratory infection caused by the Bordetella pertussis or Bordetella parapertussis bacteria. It is a serious disease that can cause permanent disability in infants, and even death.

When an infected person sneezes or coughs, tiny droplets containing the bacteria move through the air, and the disease is easily spread from person to person. Initial symptoms, similar to the common cold, usually develop about a week after exposure to the bacteria. Severe episodes of coughing start about 10 to 12 days later. In children, the coughing often ends with a "whoop" noise. The sound is produced when the patient tries to take a breathe. The whoop is rare in patients under 6 months of age and in adults. Coughing spells may lead to vomiting. Pertussis should always be considered when vomiting occurs with coughing. In infants, choking spells are common.

The infection usually lasts 6 weeks.

Whooping cough can affect people of any age. Before vaccines were widely available, the disease was most common in infants and young children. Now that most children are immunized before entering school, the higher percentage of cases is seen among adolescents and adults.

Symptoms:
  • Runny nose
  • Slight fever (102°F or lower)
  • Severe, repeated coughs that:
    • Make breathing difficult
    • Result in vomiting
    • Produce a high-pitched "whooping" sound when a person takes a breath
    • Cause a short loss of consciousness
  • Diarrhea
  • Choking spells in infants
Signs and tests:

The initial diagnosis is usually based on the symptoms. However, when the symptoms are not obvious, pertussis may be difficult to diagnose. In very young infants, the symptoms may be caused by pneumonia instead.

To know for sure, the health care provider may take a sample of mucus from the nose nasal secretions and send it to a lab, which tests it for pertussis. While this can offer an accurate diagnosis, the test some time, and treatment is usually started before the results are ready.

Some patients may have a complete blood count that shows large numbers of lymphocytes.


Review Date: 10/23/2007
Reviewed By: Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor of Pediatrics, NYU School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network.

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