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Bleeding disorders

Bleeding disorders


Definition:

Bleeding disorders are a group of conditions involving the body's blood clotting process. Such disorders can lead to heavy and prolonged bleeding after an injury.

Alternative Names:
Coagulopathy

Problems can occur when certain coagulation factors are low or missing. Bleeding problems can range from mild to severe.

Some bleeding disorders are present at birth and are passed through families (inherited). Others develop during certain illnesses (such as vitamin K deficiency or severe liver disease), or treatments (such as the use of drugs to stop blood clots (anticoagulants) or the long-term use of antibiotics).

Bleeding disorders can also result from having poorly working or too few of the blood cells that promote blood clotting (platelets). These disorders can also be either inherited or picked up (acquired). The side effects of certain drugs often lead to the acquired forms.

Causes, incidence, and risk factors:

Normal blood clotting involves as many as 20 different plasma proteins, which are known as blood clotting or coagulation factors. These factors act together with other chemicals to form a substance called fibrin that stops bleeding.

Blood clotting
Blood clotting
Symptoms:
  • Abnormal menstrual bleeding
  • Bleeding into joints
  • Excess bruising
  • Heavy bleeding
  • Nose bleeds

See also:

Signs and tests:
  • Complete blood count may show low platelets or anemia
  • Prothrombin time (PT) may be longer
  • Partial thromboplastin (PTT) time may be longer
  • Bleeding time may be longer
  • Platelet aggregation test may be abnormal

Which abnormalities occur depends on the bleeding disorder.


Review Date: 3/13/2007
Reviewed By: Mark Levin, M.D., Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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