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 General Gastroenterology

Plummer-Vinson syndrome/esophageal web

Plummer-Vinson syndrome/esophageal web

Esophagus and stomach anatomy
Esophagus and stomach anatomy

Definition:

Plummer-Vinson syndrome consists of chronic iron deficiency anemia, difficulty swallowing, esophageal webs, and other, less common abnormalities. Esophageal webs are small, thin growths of tissue that partially block the esophagus (food pipe). They cause difficulty swallowing, and tend to be located in the middle or upper esophagus.

Alternative Names:
Paterson-Kelly syndrome; Sideropenic dysphagia
Causes, incidence, and risk factors:

The cause of Plummer-Vinson syndrome is unknown. Genetic factors and nutritional deficiencies may play a role. It is a rare disorder that is often connected with cancer of the esophagus and throat.

Symptoms:
  • Difficulty swallowing
  • Weakness
Signs and tests:

Upper GI series or upper endoscopy may reveal the web. Tests to diagnose anemia and/or iron deficiency may be useful.

Some patients develop skin and nail abnormalities that can be identified by a doctor during an examination.


Review Date: 10/13/2006
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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