List of Topics Print This Page

 Infectious Diseases

Lymphogranuloma venereum

Lymphogranuloma venereum

Lymphatic system
Lymphatic system

Definition:

Lymphogranuloma venereum (LGV) is a sexually transmitted disease (STD) caused by the bacteria Chlamydia trachomatis.

Alternative Names:
LGV; Lymphogranuloma inguinale; Lymphopathia venereum
Causes, incidence, and risk factors:

Lymphogranuloma venereum (LGV) is caused by three different sub-types of the bacteria Chlamydia trachomatis. The bacteria is spread through sexual contact. (Note: This infection is caused by a different bacteria than the more common genital chlamydia.)

Symptoms of LGV can begin a few days to a month after becoming infected. It more common in Central and South America than in North America. There are a few thousand cases of LGV each year in the United States. The main risk factor is having multiple sexual partners.

The disease starts as a painless ulcer on the male genitalia or in the female genital tract. As the bacteria spreads, lymph nodes in the area become swollen and tender. The skin around the area is often red. The swollen lymph nodes (buboes) may break open and drain through the skin.

In people who have anal intercourse, the disease can affect the lymph nodes around the rectum (perirectal). The infection is often associated with bloody rectal discharge, painful bowel movement (tenesmus), diarrhea, and lower abdominal pain. Women may develop fistulas (connections) between the vagina and rectum.

Symptoms:
  • Small painless ulcer on genitalia
  • Swelling and redness of the skin in the groin area
  • Swollen groin lymph nodes on one or both sides
  • Drainage from lymph nodes in groin
  • Blood or pus from the rectum (blood in the stools)
  • Pain while having a bowel movement (tenesmus)
Signs and tests:

The medical history and physical examination may show:

  • A history of sexual contact with a person having lymphogranuloma venereum
  • An ulcer on an affected person's genitals
  • A perianal fistula with drainage
  • Swollen lymph nodes in the groin (inguinal lymphadenopathy)
  • Drainage from lymph nodes in the groin
Tests may include:
  • Biopsy of the node
  • Indirect immunofluorescence for chlamydia
  • Serology test for LGV

Review Date: 10/9/2006
Reviewed By: D. Scott Smith, M.D., MSc, DTM&H, Chief of Infectious Disease & Geographic Medicine, Kaiser Redwood City, CA & Adjunct Assistant Professor, Stanford University. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

  View History
 Lymphogranuloma venereum

   
   

 

About UPHS   Contact Us   Site Map   Privacy Statement   Legal Disclaimer   Terms of Use

The University of Pennsylvania Health System, Philadelphia, PA 1-800-789-PENN © 2009, The Trustees of the University of Pennsylvania