Caplan syndrome is caused by breathing in mining dust, which causes inflammation and can lead to the development of many small lung bumps (nodules) and mild asthma-like airway disease. Some people who have been exposed to the dust have severe lung scarring that makes it difficult for their lungs to carry oxygen to the bloodstream (called progressive massive fibrosis). People with rheumatoid arthritis do not seem more likely to have this complication of scarring. Caplan syndrome is very rare in the United States. |