Penn Cardiac Care

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Clinical Activity Report

Cardiovascular Surgery Division review
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Electrophysiology
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Heart Failure & Transplantation:

Destination Therapy & Permanent VADs

Ventricular Assist Devices

Heart Transplants
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Ventricular Assist Devices (VADs)

The Heart Failure and Transplantation Program at Penn is the region's leading advocate for the use of VADs in patients in end-stage heart failure and those awaiting heart transplantation, and is a primary force in clinical research for these devices.

An overview of the devices currently available – or soon to be available – at Penn offers an inventory of the world's most sophisticated VADs, and a glimpse of what the future may hold for end-stage heart failure and heart transplantation patients.

Types of VAD Implantations, 1995-2006


Case Study

Mr. M, a 28-year-old male, suffered an acute MI near his home. He was taken to a community hospital ER, where an emergency catheterization revealed an extensive occlusion of his LAD. When a subsequent angioplasty failed to improve his hemodynamics, Mr. M was transferred directly to an operating room at the Hospital of the University of Pennsylvania via PennSTAR.

There, he received a Thoratec Paracorporeal LVAD to support his failing heart. During his recovery in the SICU, a PET scan revealed massive myocardial destruction. Mr. M was listed for transplantation, and after 46 days of VAD support, underwent a successful transplant. Today, he has returned to his work as an historical researcher.

Clinical Trials

VentrAssist™ is a new third generation cardiac assist system primarily designed as a permanent alternative to heart transplants for patients suffering heart failure. It can be used as a bridge to heart transplant and possibly as a bridge to recovery, where it may allow a deteriorating heart an opportunity to recuperate. This trial will begin in Fall 2007.

  • VentrAssist™ Left Ventricular Assist Device as Bridge to Cardiac Transplantation
  • VentrAssist™ Left Ventricular Assist Device for the Treatment of Advanced Heart Failure Destination Therapy

 


 

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